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Methotrexate is an antimetabolite medicine, as it impacts cell metabolic process. It can be prescribed for managing active rheumatoid arthritis, breast cancer cells, skin psoriasis, and a few other disorders related to fast and abnormal growth of cells in the body. This medication could be administered by mouth, along with infused intramuscularly or intravenously. Methotrexate is most often offered weekly, unless suggested otherwise by the doctor.

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